Tag Archives: studies

Biomed Approach to Alzheimer’s Disease?

psychedelic

Alzheimer’s is one of those ‘mysteries’ like autism- but we now know that many kids can recover from autism with what is called a biomedical or ‘biomed’ approach that addresses underlying biological dysfuntions that result in physical or behavioral symptoms. Could adults also recover from Alzheimer’s, or at least halt its progression, with a biomed approach? Some of you may be familiar with NAC (N-acetyl cysteine) and its use in ASD- but look at these results on Alzheimer’s mice!
” The results showed that the mice pretreated with NAC had significantly greater retention in the step through test and shorter latencies in the water maze performance.”
Biochemical markers were also reversed or reduced with NAC pre-treatment.

There was another study that looked at a combo of NAC and acetyl-L-carnitine and S-adenosyl methionine on AD mice, too, with good results.
Behavioral abnormalities correlated with a decline in acetylcholine, which was also prevented by this nutriceutical combination, suggesting that neurotransmitter imbalance may contribute to their manifestation.

What brought me down this trail was looking at factors in RLS (which I have) and often it has to do with low iron or low oxygen transport and this is why iron supplements often help. Didn’t help for me, and neither did any of the other usual things like B vitamins, calcium, magnesium, etc. Usually, smoking makes RLS worse but in some cases, it oddly helps (including for me), and it turns out this is true for a subset of RLS patients and also Parkinsons’ patients, and the connection has to do with acetylcholine, a neurotransmitter.

On a side note, PD drugs like Requip are also used for RLS. These drugs are not that much more effective than placebos and carry the risk of serious side-effects, but perhaps they do work for a subset of RLS patients whose symptoms have to do with an underlying mechanism of action involving the same neurotransmitters that are involved in Parkinson’s Disease. They target dopamine receptors, which are also known to be defective in some patients with Alzheimer’s Disease, who have PD-type symptoms along with their AD.

RLS itself is also sometimes an early warning sign of AD (hope to God that’s not my situation). So there is this connection with both Alzheimer’s and Parkinson’s and RLS, and a connection with improvement in PD and RLS symptoms with nicotine.There has also been some research showing that nicotine patches slightly improve memory in pre-demetia patients.

So we have scientific evidence that nicotine helps alleviate symptoms in some sufferers of AD, PD, and RLS. We also have evidence that these symptoms are related to acetylcholine levels, and that NAC normalizes acetylcholine levels in AD mice. What is the connection with nicotine and acetylcholine?
Nicotine imitates the action of a natural neurotransmitter called acetylcholine and binds to a particular type of acetylcholine receptor, known as the nicotinic receptor.
thebrain.mcgill.ca

I’m not recommending that anyone with RLS, PD, or AD take up smoking. In fact, I’m not recommending anything. But as you see, there is this connection with acetylcholine, RLS, AD and PD. So can it be prevented or reversed? You may have heard of coconut oil for AD but that is another story. Here are the mouse studies on NAC and other natural substances that raise glutathione and affect neurotransmitters and the doses are high but the results look promising and so do studies on NAC for AD in humans. Maybe one day, Alzheimer’s treatment will be focused on using neutraceuticals like NAC. Or maybe not, since there is no big money to be made in that.

For now, preliminary research in mice looks good and I hope we see more human studies on this soon!

http://www.mccordresearch.com/sites/default/files/research/NAC_and_Learning_and_Memory.pdf

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952755/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830120/

http://www.neurology.org/content/57/8/1515.short
http://www.ncbi.nlm.nih.gov/pubmed/17914184

http://www.nature.com/npp/journal/v19/n6/abs/1395227a.html

http://thebrain.mcgill.ca/flash/i/i_03/i_03_m/i_03_m_par/i_03_m_par_nicotine.html

Image courtesy of Salvatore Vuono / FreeDigitalPhotos.net

Disclaimer: the content of this article is for information purposes only and is not to be construed as medical advice.

Scientific Evidence of Vaccine Damage in Dogs

Although many parents witness their children’s health deteriorate rapidly after vaccination, we are repeatedly told that there is no evidence that vaccines cause damage. The main reason this claim can be made is that there has never been a study done on humans that compared the vaccinated to the unvaccinated. The control group either receives a different experimental vaccine or regular ‘baby shots’. The closest we can get to seeing the true extent of the damage that vaccines do is through animal studies. While it is hard to find raw data from animal studies that are done for the purpose of testing a vaccine ultimately to be marketed to humans, some studies done on the effects of vaccines on dogs and monkeys are avaiable to us, and the results don’t look good.

The following link will take you to a summary of the evidence of vaccine damage on dogs. Aside from the fact that you can extrapolate the results to mean that vaccines likely cause such damage in humans as well, isn’t this enough to make you re-think vaccinating your pet?

http://www.dogsadversereactions.com/scienceVaccineDamage.html

Here is an excerpt from the report:

The vaccinated, but not the non-vaccinated, dogs in the Purdue studies developed autoantibodies to many of their own biochemicals, including fibronectin, laminin, DNA, albumin, cytochrome C, cardiolipin and collagen.

This means that the vaccinated dogs — ”but not the non-vaccinated dogs”– were attacking their own fibronectin, which is involved in tissue repair, cell multiplication and growth, and differentiation between tissues and organs in a living organism.

The vaccinated Purdue dogs also developed autoantibodies to laminin, which is involved in many cellular activities including the adhesion, spreading, differentiation, proliferation and movement of cells. Vaccines thus appear to be capable of removing the natural intelligence of cells.

Dogs and cats, like our children, are more and more often falling victim to auto-immune diseases and cancer. In recent years, reports of ‘autistic’ dogs have even surfaced. Whether you have a pet or a child, you owe it to them to make an informed decision when it comes to vaccinating them. And likely, if you are truly informed, you will find that you cannot possibly submit them to this kind of assault.